Antidepressants and Receptor Function : Novartis Foundation Symposia Series, Book 705 (eBook)
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Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy 1986 Depression is a common and often debilitating affective disorder. Attempts to develop effective antidepressants have a long history, but many questions remain about the mechanisms of action of such treatments and about the aetiology and pathophysiology of depression itself. Early observations centred attention on central monoamine systems, and animal studies suggested that changes in beta-adrenoceptor responsiveness were a common effect of antidepressant therapies. More recent research has encompassed many different central and peripheral receptors, time-dependent adaptational events at synapses, and the functional significance of changes in neurotransmitter systems in both humans and experimental animals. Such pharmacological studies aimed ultimately at elucidating the neurochemical basis of depression and of promoting new therapeutic approaches, provide the focus of this symposium v...

 
 
 
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  • ISBN: 9780470513378
  • Publisher: John Wiley & Sons, Ltd.
  • Imprint: John Wiley & Sons, Inc.
  • Date: Apr 2008
 
 
 
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