Folate Transport & DNA Methylation : The Molecular Approach
by Abid Hamid Dar


Overview - The folate transport system reflects complex regulatory mechanism of diverse biochemical and physiological nature at the absorptive epithelia dictated by the site and tissue specific microenvironment. The author studied the alcohol associated changes on DNA methylation which explains the etiology of the cancer via epigenetic mechanisms.  Read more...

 
In Stock.

This item is Non-Returnable.
FREE Shipping for Club Members
 
> Check In-Store Availability

In-Store pricing may vary

 
 
New & Used Marketplace 4 copies from $82.06
 
 
 

More About Folate Transport & DNA Methylation by Abid Hamid Dar
 
 
 
Overview
The folate transport system reflects complex regulatory mechanism of diverse biochemical and physiological nature at the absorptive epithelia dictated by the site and tissue specific microenvironment. The author studied the alcohol associated changes on DNA methylation which explains the etiology of the cancer via epigenetic mechanisms. Here insights in the role that reduced folate carrier and folate binding protein play in folate delivery across epithelia in conditions of malabsorption has been primarily explained at molecular level. In addition, disruption of the epigenome by extremes of dietary folates in human tissue recombination xenograft/orthotopic models using mesenchymal stem cells for cancer development and progression has also been highlighted. The knowledge regarding the expression, intracellular regulation and localization of carriers in relation to their role in the transport of folate might be useful for development of future therapeutic strategies for counteracting the clinical findings of folate deficiency. This work was carried out at the India's Premier Medical Science Institute-Postgraduate Institute of Medical Education & Research, Chandigarh India.


This item is Non-Returnable.

 
Details
  • ISBN-13: 9783847334989
  • ISBN-10: 3847334980
  • Publisher: LAP Lambert Academic Publishing
  • Publish Date: January 2012
  • Page Count: 192
  • Dimensions: 9 x 6 x 0.44 inches
  • Shipping Weight: 0.64 pounds


Related Categories

Books > Science > Life Sciences - Biochemistry

 
BAM Customer Reviews