A New York Times Notable Book
A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies --a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to "read" and "write" our own genetic information? Read more...
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ProductsMore About The Gene by Siddhartha MukherjeeOverviewTHE #1 NEW YORK TIMES BESTSELLER
A New York Times Notable Book
A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies--a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to "read" and "write" our own genetic information? Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. Throughout the narrative, the story of Mukherjee's own family--with its tragic and bewildering history of mental illness--cuts like a bright, red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation--from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. As The New Yorker said of The Emperor of All Maladies, "It's hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion...An extraordinary achievement." Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or "write" the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.
Publishers Weekly Reviews
Publishers Weekly® Reviews
- Reviewed in: Publishers Weekly, page .
- Review Date: 2016-02-29
- Reviewer: Staff
In skillful prose, Mukherjee, an oncologist and the Pulitzer Prize–winning author of The Emperor of All Maladies, relates the grand tale of how scientists have come to understand the role genes play in human development, behavior, and physiology. He deftly relates the basic scientific facts about the way genes are believed to function, while making clear the aspects of genetics that remain unknown. Mukherjee offers insight into both the scientific process and the sociology of science, exploring the crucial experiments that have shed light on the biochemical complexities inherent in the genome. He also examines many of the philosophical and moral quandaries that have long swirled around the study of genetics, addressing such important topics as eugenics, stem cell research, and what it means to use the composition of a person's genotype to make predictions about his or her health or behavior. Looking to the future, Mukherjee addresses prospects for medical advances in the treatment of diseases and in selecting—or actively crafting—the genetic composition of offspring, regularly pointing out the pressing ethical considerations. Throughout, he repeatedly poses the question, "What is ‘natural'?" declining to offer a single answer, in recognition that both context and change are essential. By relating familial information, Mukherjee grounds the abstract in the personal to add power and poignancy to his excellent narrative. (May)