Artificial Intelligence in Label-Free Microscopy : Biological Cell Classification by Time Stretch
Overview
This book introduces time-stretch quantitative phase imaging (TS-QPI), a high-throughput label-free imaging flow cytometer developed for big data acquisition and analysis in phenotypic screening. TS-QPI is able to capture quantitative optical phase and intensity images simultaneously, enabling high-content cell analysis, cancer diagnostics, personalized genomics, and drug development. The authors also demonstrate a complete machine learning pipeline that performs optical phase measurement, image processing, feature extraction, and classification, enabling high-throughput quantitative imaging that achieves record high accuracy in label -free cellular phenotypic screening and opens up a new path to data-driven diagnosis.
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Details
- ISBN-13: 9783319514475
- ISBN-10: 3319514474
- Publisher: Springer
- Publish Date: April 2017
- Dimensions: 9.21 x 6.14 x 0.44 inches
- Shipping Weight: 0.92 pounds
- Page Count: 134
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