{ "item_title" : "Brain Function and Dysfunction", "item_author" : [" Anand Madhu "], "item_description" : "Alzheimer's Disease is rapidly increasing in prevalence. This pandemic of the post-industrial age wreaks havoc on the elderly people (some as young as 40), particularly in the richer and more powerful nations. With only a few weak hypotheses, its cause is not understood; all proposed medicines have either failed clinical trials or proven ineffective. In this book, I lay out a new, relatively stronger and more broad-based theory of dementia causation, exploring beyond Matsuyama's 1989 theory that held pervasive Microtubule collapse to be a key characteristic of dementia. In brief: Psychological functions are carried out by neurocircuits containing myriads of Dopaminergic and Norepic systems; due to excessive electrical signalling in dopamine-heavy types of brains -- the signal conducting micro-tubules break down, causing the neuronal collapse which characterizes dementia. More the signalling volume, more the stress (either mechanical and/or thermal and/or chemical stress), which proves fatal in the end.", "item_img_path" : "https://covers4.booksamillion.com/covers/bam/8/19/235/597/8192355977_b.jpg", "price_data" : { "retail_price" : "7.62", "online_price" : "7.62", "our_price" : "7.62", "club_price" : "7.62", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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