{ "item_title" : "CAR-T Cell Therapy for Leukemia and Lymphoma", "item_author" : [" 翟志敏 主编 "], "item_description" : "Analyze typical cases of leukemia and lymphoma to understand the entire process of CAR-T cell therapy. 分析白血病和淋巴瘤典型病例，了解CAR-T细胞治疗全过程 Chimeric antigen receptor T-cells, referred to as CAR-T (chimeric antigen receptor T-cell), are special cells derived from ordinary T cells that have been genetically engineered to express targeted receptors. They possess the ability to specifically recognize and kill tumor cells, and are therefore known as living cell drugs. The editors of this book are frontline physicians who have directly participated in clinical research and been responsible for the entire process management of patients. They are also among the earliest teams in China to conduct CAR-T cell therapy for leukemia and lymphoma. This book is divided into three parts: Part I systematically introduces the basic theory, clinical procedures and methods, as well as the existing problems and challenges of CAR-T cell therapy. Parts II and III present 20 uniquely significant cases selected and analyzed from over 100 cases of relapsed/refractory leukemia and lymphoma treated with CAR-T cell therapy at the editors' medical center. The book focuses on the diagnosis and treatment process of each selected case, and provides in-depth analysis of the particularities, successful experiences, possible causes of failure, and potential solutions for each case, based on domestic and international clinical study results or recent advances. This book presents cutting-edge content and real cases, serving as a valuable reference for clinicians and researchers who are confused, concerned about, or interested in the use of CAR-T cell therapy. 嵌合抗原受体T细胞简称CAR-T（chimeric antigen receptor T-cell），是一种将普通T细胞经基因工程技术改造之后表达靶向受体的特殊细胞，具有特异性识别和捕杀肿瘤细胞的特点，被称为细胞活药。 本书编者均是直接参与临床研究并负责患者全程管理的一线医生，也是国内最早开展CAR-T细胞治疗白血病和淋巴瘤的团队之一。本书共分为三部分：第一部分系统地介绍了CAR-T细胞治疗技术的基础理论、临床操作程序与方法，以及存在的问题和挑战；第二、三部分主要从编者所在医疗中心采用CAR-T细胞治疗过的100多例复发/难治性白血病和淋巴瘤病例中，梳理、筛选出20个具有独特意义的病例进行分析和讨论。书中重点介绍了所选病例的诊疗过程，并结合国内外报道的临床研究结果或最新进展，从不同角度深度剖析了每个病例的特殊性、成功经验或可能的失败原因及有望解决的方案等。 本书内容前沿，案例真实，可为对使用CAR-T细胞治疗感到困惑、担忧，或对此感兴趣的临床医生和研究者提供借鉴和参考。", "item_img_path" : "https://covers3.booksamillion.com/covers/bam/7/54/786/407/7547864074_b.jpg", "price_data" : { "retail_price" : "27.99", "online_price" : "27.99", "our_price" : "27.99", "club_price" : "27.99", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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