{ "item_title" : "Computational Methods for Estimating the Kinetic Parameters of Biological Systems", "item_author" : [" Quentin Vanhaelen "], "item_description" : "1. Current Approaches of Building Mechanistic Pharmacodynamic Drug-Target Binding ModelsJingyi Liang, Vi Ngoc-Nha Tran, Colin Hemez, and Pia Abel zur Wiesch2. An Extended Model Including Target Turnover, Ligand-Target Complex Kinetics, and Binding Properties to Describe Drug-Receptor InteractionsLambertus A. Peletier3. Beyond the Michaelis-Menten: Bayesian Inference for Enzyme Kinetic AnalysisHyukpyo Hong, Boseung Choi, and Jae Kyoung Kim4. Multi-Objective Optimization Tuning Framework for Kinetic Parameter Selection and EstimationYadira Boada, Jes s Pic , and Alejandro Vignoni5. Relationship between Dimensionality and Convergence of Optimization Algorithms: A Comparison between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI Andrea Degasperi, Lan K. Nguyen, Dirk Fey, and Boris N. Kholodenko6. Dynamic Optimization Approach to Estimate Kinetic Parameters of Monod-Based Microalgae Growth ModelsSiti S. Jamaian, Fathul H. Zulkifli, and Kim S. Ling7. Automatic Assembly and Calibration of Models of Enzymatic Reactions Based on Ordinary Differential EquationsJure Stojan, Milan Hodosček, and Dusanka Janezič8. Data Processing to Probe the Cellular Hydrogen Peroxide LandscapeFernando Antunes and Paula Brito9. Computational Methods for Structure-Based Drug Design through Systems BiologyAman Chandra Kaushik, Shakti Sahi, and Dong-Qing Wei10. Model Setup and Procedures for Prediction of Enzyme Reaction Kinetics with QM-Only and QM: MM ApproachesMichal Glanowski, Sangita Kachhap, Tomasz Borowski, and Maciej Szaleniec11. The Role of Ligand Rebinding and Facilitated Dissociation on the Characterization of Dissociation Rates by Surface Plasmon Resonance (SPR) and Benchmarking Performance MetricsAykut Erbaş and Fatih Inci12. Computational Tools for Accurate Binding Free Energy PredictionMaria M. Reif and Martin Zacharias13. Computational Alanine Scanning Reveals Common Features of TCR/pMHC Recognition in HLA-DQ8-Associated Celiac DiseaseLinqiong Qiu, Jianing Song, and John Z.H. Zhang14. Umbrella Sampling-Based Method to Compute Ligand-Binding AffinitySon Tung Ngo and Minh Quan Pham15. Creating Maps of the Ligand Binding Landscape for Kinetics-Based Drug DiscoveryTom Dixon, Samuel D. Lotz, and Alex Dickson16. Prediction of Protein-Protein Binding Affinities from Unbound Protein Structures&nb", "item_img_path" : "https://covers4.booksamillion.com/covers/bam/1/07/161/766/1071617664_b.jpg", "price_data" : { "retail_price" : "249.99", "online_price" : "249.99", "our_price" : "249.99", "club_price" : "249.99", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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