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Genetics, Trauma, and the Brain|Patrick Di Santo

Genetics, Trauma, and the Brain : The Fragile Thread

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Overview

This groundbreaking volume investigates the subtle and often overlooked connections between genetic variation, trauma, and brain development. Drawing on clinical case studies, chromosomal microarray findings, and gene-environment models, the authors explore how neurodevelopmental outcomes are shaped by early-life stressors--including even mild traumatic brain injury--and how these exposures can alter emotional, cognitive, and academic trajectories across the lifespan.

Accessible to both practitioners and general readers, the book introduces key mechanisms such as FGGY-PTEN (phosphatase and tensin homolog) signaling and absence of heterozygosity, while also highlighting the social and structural factors that intensify vulnerability. A regional focus on underserved and rural populations underscores the need for early detection and targeted care.

Designed for clinicians, educators, genetic counselors, and public health advocates, this book builds a vital bridge between molecular insight and practical intervention, arguing that prevention and precision care must begin far earlier than current systems allow.

This item is Non-Returnable

Details

  • ISBN-13: 9781036475741
  • ISBN-10: 1036475743
  • Publisher: Cambridge Scholars Publishing
  • Publish Date: August 2026
  • Dimensions: 8 x 6 x 0.9 inches
  • Shipping Weight: 1.2 pounds
  • Page Count: 352

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