{
"item_title" : "Introduction to Statistical Methods for Clinical Trials",
"item_author" : [" Thomas D. Cook", "David L. Demets "],
"item_description" : "This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS.",
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Overview
This text provides a solid understanding of the various statistical topics relevant to the design, monitoring, and analysis of a clinical trial. It covers basic experimental design, sample size, randomization procedures, interim and survival analyses, quality of life assessment, and longitudinal methods. The book describes all phases of a clinical trial and explores the advantages of and objections to the intent-to-treat principle as well as its implementation. With exercises at the end of most chapters, it also illustrates methods using examples with real data from a variety of disease areas, including heart and lung diseases, cancer, and AIDS.
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Details
- ISBN-13: 9781584880271
- ISBN-10: 1584880279
- Publisher: CRC Press
- Publish Date: November 2007
- Dimensions: 9.3 x 6.4 x 1.2 inches
- Shipping Weight: 1.7 pounds
- Page Count: 464
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