{ "item_title" : "Pharmaceutical Formulation Development of Peptides and Proteins", "item_author" : [" Lars Hovgaard", "Sven Frokjaer", "Marco Van de Weert "], "item_description" : "The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products.Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therapeutic peptides and proteins, from the production of active compounds via basic pre-formulation and formulation to the registration of the final product.Providing integrated solutions, this book discusses:The synthesis of peptides and the biotechnological production of proteins through recombinant DNA technologyThe physicochemical characteristics and stability of peptides and proteinsThe formulation of proteins as suspensions, solutions, and (mostly freeze-dried) solidsThe opportunities and challenges of non-parenteral delivery of peptides and proteinsRisk factors, specifically the development of an unwanted immune responseA simulation approach to describe the fate of peptides and proteins upon administration to a biological systemThe documentation required to register a protein-based drugScientists in the pharmaceutical industry and academia as well as postgraduate students in pharmaceutical science will find this a valuable resource.", "item_img_path" : "https://covers4.booksamillion.com/covers/bam/1/43/985/388/1439853886_b.jpg", "price_data" : { "retail_price" : "280.00", "online_price" : "280.00", "our_price" : "280.00", "club_price" : "280.00", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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