Phenotypes and Genotypes : The Search for Influential Genes
Overview
This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
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Details
- ISBN-13: 9781447153092
- ISBN-10: 144715309X
- Publisher: Springer
- Publish Date: February 2016
- Dimensions: 9.21 x 6.14 x 0.56 inches
- Shipping Weight: 1.12 pounds
- Page Count: 222
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