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{ "item_title" : "Systems Genetics", "item_author" : [" Florian Markowetz", "Michael Boutros "], "item_description" : "Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.", "item_img_path" : "https://covers1.booksamillion.com/covers/bam/1/10/879/459/1108794599_b.jpg", "price_data" : { "retail_price" : "53.00", "online_price" : "53.00", "our_price" : "53.00", "club_price" : "53.00", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }
Systems Genetics|Florian Markowetz

Systems Genetics : Linking Genotypes and Phenotypes

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Overview

Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.

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Details

  • ISBN-13: 9781108794596
  • ISBN-10: 1108794599
  • Publisher: Cambridge University Press
  • Publish Date: April 2020
  • Dimensions: 9.61 x 6.69 x 0.57 inches
  • Shipping Weight: 0.96 pounds
  • Page Count: 272

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