Tandem Repeat Polymorphisms : Genetic Plasticity, Neural Diversity and Disease
Overview
Tandem Repeat Polymorphisms: Mediators of Genetic Plasticity, Modulators of Biological Diversity and Dynamic Sources of Disease Susceptibility.- Evolution of Simple Sequence Repeats as Mutable Sites.- Single Amino Acid and Trinucleotide Repeats: Function and Evolution.- Promoter Microsatellites as Modulators of Human Gene Expression.- Dynamic Mutations: Where Are They Now.- Unstable Mutations in the FMR1 Gene and the Phenotypes.- Molecular Pathways to Polyglutamine Aggregation.- Polyglutamine Aggregation in Huntington and Related Diseases.- Selective Neurodegeneration, Neuropathology and Symptom Profiles in Huntington's Disease.- Kennedy's Disease: Clinical Significance of Tandem Repeat s in the Androgen Receptor.- Characterising the Neuropathology and Neurobehavioural Phenotype in Friedreich Ataxia: A Systematic Review.- Polyalanine Tract Disorders and Neurocognitive Phenotypes.
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Details
- ISBN-13: 9781493954483
- ISBN-10: 1493954482
- Publisher: Springer
- Publish Date: August 2016
- Dimensions: 10 x 7 x 0.49 inches
- Shipping Weight: 0.9 pounds
- Page Count: 208
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