{ "item_title" : "Taurine 4", "item_author" : [" Laura Della Corte", "Ryan J. Huxtable", "Giampietro Sgaragli "], "item_description" : "Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ( Ca ]), mitochondria accumulate Ca until theCa ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ TheCa ] at which the uniporter and efflux activities are equal is defined o the setpoint andcorresponds to values between 0.3-3 M. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. membrane potential. ? pH gradient. Adapted from .", "item_img_path" : "https://covers3.booksamillion.com/covers/bam/0/30/646/447/0306464470_b.jpg", "price_data" : { "retail_price" : "219.99", "online_price" : "219.99", "our_price" : "219.99", "club_price" : "219.99", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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