{ "item_title" : "Testing for BNP and NT-proBNP in the Diagnosis and Prognosis of Heart Failure", "item_author" : [" Agency for Healthcare Resea And Quality", "U. S. Department of Heal Human Services "], "item_description" : "B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are promising markers for heart failure diagnosis, prognosis, and treatment. This systematic review addresses these four main questions: 1. What are the determinants of both BNP and NT-proBNP measurement? 2. With respect to the diagnosis of heart failure: a. What are the clinical performance characteristics of both BNP and NT-proBNP measurement in patients with symptoms suggestive of heart failure (HF) or with known HF i. presenting to the emergency department (ED) ii. in a specialized clinic or outpatient setting iii. presenting to a primary care setting iv. presenting in long term care setting v. all settings combined b. Does measurement of BNP or NT-proBNP add independent diagnostic information to the traditional diagnostic measures of HF in patients with symptoms suggestive of HF? 3. Do BNP or NT-proBNP levels predict cardiac events in populations: a. Specific populations i. at risk for coronary artery disease (CAD) ii. with diagnosed CAD iii. with diagnosed HF b. What are the screening characteristics of BNP or NT-proBNP in general asymptomatic populations? 4. Can BNP or NT-proBNP measurement be used to monitor response to therapy?", "item_img_path" : "https://covers2.booksamillion.com/covers/bam/1/50/035/052/1500350524_b.jpg", "price_data" : { "retail_price" : "31.99", "online_price" : "31.99", "our_price" : "31.99", "club_price" : "31.99", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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