{ "item_title" : "Transformative Concepts for Drug Design", "item_author" : [" Ariel Fernandez "], "item_description" : "Protein Cooperativity and Wrapping: Two Themes in the Transformative Platform of Molecular Targeted Therapy.- Wrapping Defects and the Architecture of Soluble Proteins.- Folding Cooperativity and the Wrapping of Intermediate States of Soluble Natural Proteins.- Wrapping Deficiencies and De-wetting Patterns in Soluble Proteins: A Blueprint for Drug Design.- Under-Wrapped Proteins in the Order-Disorder Twilight: Unraveling the Molecular Etiology of Aberrant Aggregation.- Evolution of Protein Wrapping and Implications for the Drug Designer.- Wrapping as a Selectivity Filter for Molecular Targeted Therapy: Preliminary Evidence.- Re-engineering an Anticancer Drug to Make It Safer: Modifying Imatinib to Curb Its Side Effects.- Wrapping Patterns as Universal Markers for Specificity in the Therapeutic Interference with Signaling Pathways.- Fulfilling a Therapeutic Imperative in Cancer Treatment: Control of Multi-target Drug Impact.- Inducing Folding By Crating the Target.- Wrapper Drugs as Therapeutic Editors of Side Effects.- Wrapper Drugs for Personalized Medicine.- Last Frontier and Back to the Drawing Board: Protein-Water Interfacial Tension in Drug Design.", "item_img_path" : "https://covers1.booksamillion.com/covers/bam/3/64/242/458/3642424589_b.jpg", "price_data" : { "retail_price" : "169.99", "online_price" : "169.99", "our_price" : "169.99", "club_price" : "169.99", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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