{ "item_title" : "Hdac/Hat Function Assessment and Inhibitor Development", "item_author" : [" Oliver H. Krämer "], "item_description" : "Part I: In Vivo and 3R Models to Assess HDAC Functions and Effects of HDACi1. Analyzing Lymphoma Development and Progression Using HDACi in Mouse ModelsEva-Maria Piskor, Ren Winkler, and Christian Kosan2. Colony Formation Assay to Test the Impact of HDACi on Leukemic CellsMiriam Pons and Mandy Beyer3. Defined Human Leukemic CD34+ Liquid Cultures to Study HDAC/Transcriptional Repressor ComplexesRoland Windisch, Sophie Kreissig, and Christian Wichmann4. Development of a Cellular Model Mimicking Specific HDAC InhibitorsLena Hess, Verena Moos, and Christian Seiser5. Evaluation of Anti-Tumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft ModelCharlotte Gatzweiler, Johannes Ridinger, Simay Ayhan, Sara Najafi, Heike Peterziel, Olaf Witt, and Ina Oehme6. Human Platelet Lysate as Valid Cell Growth Additive to Assess Protein AcetylationMiriam Pons, Roland Conradi, Walburgis Brenner, and Oliver H. Kr mer7. Investigating Physiopathological Roles for Sirtuins in a Mouse ModelShimin Sun, Xiaojiao Xia, Ming Wang, and Baohua Liu8. Patient-Derived Organoids for In Vivo Validation of In Vitro DataSaid Kdimati, Florian B rtin, Michael Linnebacher, and Christina Susanne MullinsPart II: Novel HDAC Inhibitors and Improved Formulations for HDAC Inhibitors9. Analysis of HDACi-Coupled Nanoparticles: Opportunities and ChallengesMarie K hne, Susanne Hofmann, Henry Lindemann, Zolt n Cseresny s, Andreas Dzierza, Daniel Schr der, Maren Godmann, Andreas Koschella, Christian Eggeling, Dagmar Fischer, Marc Thilo Figge, Thomas Heinze, and Thorsten Heinzel10. Development of Pyrazine-Anilinobenzamides as Histone Deacetylase HDAC1-3 Selective Inhibitors and Biological Testing Against Pancreas Cancer Cell LinesMohamed Abdelsalam, Hany S. Ibrahim, Lukas Krauss, Matthes Zessin, Anita Vecchio, Sieglinde Hastreiter, Mike Schutkowski, G nter Schneider, and Wolfgang Sippl11. Evaluation of Small Molecule HDAC Inhibitors through In Vitro and In Cellulo ApproachesNabanita Nawar, Harsimran Kaur Garcha, Abootaleb Sedighi, Elvin D. de Araujo, and Patrick T. Gunning12. Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting ChimerasSalma Darwish, Tino Heimburg, Johannes Ridinger, Daniel Herp, Matthias Schmidt, Christophe Romier, Manfred Jung, Ina Oehme, and Wolfgang Sippl13. HDACi Delivery Systems Based on Cellulose Valproate NanoparticlesHenry Lindemann, Marie K hne, Andreas Koschella, Maren Godmann, Thorsten Heinzel, and Thomas Heinze", "item_img_path" : "https://covers2.booksamillion.com/covers/bam/1/07/162/787/1071627872_b.jpg", "price_data" : { "retail_price" : "219.99", "online_price" : "219.99", "our_price" : "219.99", "club_price" : "219.99", "savings_pct" : "0", "savings_amt" : "0.00", "club_savings_pct" : "0", "club_savings_amt" : "0.00", "discount_pct" : "10", "store_price" : "" } }

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